NIH Awards $1.2 Million To Study Protein Misfolding Diseases

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Posted by Cystic Fibrosis News From Medical News Today | Posted in Biology / Biochemistry | Posted on 03-09-2010

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Cystic Fibrosis News From Medical News Today

Three University of Massachusetts Amherst scientists have received a four-year, $1.2 million EUREKA grant from the U.S. National Institutes of Health (NIH) to study folding and misfolding of secretory proteins in the cell's protein factory, the endoplasmic reticulum, where misfolding can lead to diseases such as cystic fibrosis and liver cirrhosis...

A Scaffold Regulating Protein Disposal Identified By MDC Researchers

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Posted by Cystic Fibrosis News From Medical News Today | Posted in Biology / Biochemistry | Posted on 14-12-2009

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How does a cell manage to identify and degrade the diverse types of defective proteins and thus protect the body against serious diseases? The researchers Sabine C. Horn, Professor Thomas Sommer, Professor Udo Heinemann and Dr. Ernst Jarosch of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, Germany, have now found a crucial piece in this puzzle...